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As we all know, the five FDA-approved medications for dementia with Alzheimer’s symptoms can only temporarily alleviate symptoms; they do not delay, stop, or reverse the disease progress.

I want you to know about a natural food supplement extracted from the sea scallop, which has been clinically proven to improve cognitive function, behavior, emotion, and life quality of Alzheimer’s and dementia patients!

I am pleased to share this promising news that comes to us from a research team  at Kyushu University in Japan led by Dr. Takehiko Fujino, Professor Emeritus of Kyushu University.

Our appreciation goes to Dr. Crystal Goh, Ph.D., Health Biotechnology, and Scientific Officer for Lifestream Group Pte Ltd., Singapore for contributing the article that we are about to enjoy.  Dr. Goh was a part of this research project.

I have reproduced the article in full as it contains much useful information and even some patient video interviews.  Here goes: 

Scallop-derived PLASMALOGEN – the most promising solution for Alzheimer’s and dementia

With a deep passion to find a solution for Alzheimer’s and dementia, Emeritus Professor Takehiko Fujino (M.D., Ph.D.) from Kyushu University in Japan recently discovered a most promising solution for Alzheimer’s and dementia – Scallop-derived PLASMALOGEN! This plasmalogen was clinically proven to improve cognitive function, behaviour, emotion and life quality of Alzheimer’s and dementia patients. Finally, a ray of hope is shining for these patients and their loved ones.

Plasmalogen – a vital component in the brain

Plasmalogens are a type of phospholipid present in almost all tissues of human beings and are most abundant in the brain. Plasmalogen level in the brain begins to increase from fetal stage and reach its peak by the 30s and start to decline thereafter.

Since 1995, researchers from Europe and US have found that Alzheimer’s patients have lower plasmalogen levels in the brain and blood serum compared to normal healthy persons. However, the research has made very little progress. In 2006, Professor Fujino and his team successfully developed a patented high-volume plasmalogen extraction method to extract 92% purity plasmalogens for animal testing and clinical trials on patients. Animal testing has shown that plasmalogens are critical for brain health and mental function. Through the animal testing, this team has discovered that plasmalogens:

  • Suppress accumulation of amyloid β proteins. These proteins will form amyloid plaque in the brain, which is one of the hallmarks of Alzheimer’s.

LPS activated accumulation of amyloid β proteins while simultaneous application of plasmalogens suppressed these proteins in the hippocampus of mice. Neurons were stained with NeuN which is shown in red (a – c). Control group treated with saline showed a slight fluorescent of amyloid β immunoreactivity (green) (d). LPS treatment increased the accumulation of amyloid β proteins (e) and these proteins were completely eradicated by plasmalogen treatment (f). Amyloid β and NeuN fluorescences were merged to show an intracellular location of amyloid β in the neurons (g and h) (Katafuchi et al., 2012).

Protect against neuronal (nerve) cell death in brain. Neuronal loss causes brain atrophy which is a prominent pathological characteristic of Alzheimer’s.

Plasmalogens inhibited hippocampal neuronal cell death in mice. Number of survived neuronal cells decreased to about 50% when cultured in nutrient-deprived medium. (A) These nutrient-deprived neuronal cells were then treated with plasmlogens for 72 hours. Survival rate significantly increased in these neuronal cells treated with plasmalogens compared with nutrient-deprived control neuronal cells. These neuronal cells were stained with Dil (red colour). Scale bar, 50 μm. (B) The bars show the number of primary hippocampal neuronal cells in the specific area of 12 randomly selected locations from each cell culture dish. The data represents average ± standard deviation from four independent experiments with significant differences between control and plasmalogen-treated groups (Bonferroni’s test, P < 0.001) (Hossain MS et al., 2013).

Improve learning and memory function. Video of this animal testing can be viewed at: https://www.facebook.com/plasmalogens/videos/1748410992114426/

 

  • Promote neurogenesis (growth of new nerve cells). Professor Fujino concludes that “It is unnecessary to improve cells destroyed by amyloid β protein if new cells are born. We believe that this very action, neurogenesis is the new treatment for dementia”.

World’s first discovery of plasmalogen-induced neurogenesis. Neurogenesis occurred in hippocampal dentate gyrus of a normal mouse resulted in denser cells (darker colour) (A). Neurogenesis did not occur in mouse with inflammation (C). After administration of plasmalogens, the condition in mouse with inflammation was restored to normal (D) as in normal mouse (B).

Clinical trial of Scallop-derived PLASMALOGEN

With impressive results from the animal testing, Professor Fujino has decided to conduct a clinical trial of plasmalogen on Alzheimer’s and dementia patients. As plasmalogen extracted from scallop is enriched with DHA and EPA and its chemical structure is closest to those found in the human body, this research team decided to use Scallop-derived PLASMALOGEN which they extracted from scallop. Scallop-derived PLASMALOGEN is completely natural without any chemical modification. In 2015, a large-scale clinical trial which involved 225 patients with moderate and severe Alzheimer’s, Lewy body, cerebrovascular and semantic dementia (60 – 85 years old) was conducted to test the effectiveness of Scallop-derived PLASMALOGEN on these patients after continuous intake for 3 months. This trial was completed in April 2016. Currently, the interim report based on 44 patients who had completed the earlier trial is available. The full data from 225 patients is expected to be published late 2016 or 2017.

Based on the clinical data from 44 patients, ingestion of Scallop-derived PLASMALOGEN replenished blood plasmalogen levels in the patients. This plasmalogen restoration therapy was proven to

  1. Improve cognitive function. 71% and 46% of patients with moderate and severe dementia respectively showed improvement in cognitive function as assessed through MMSE test. MMSE is a test that is used internationally to help in the diagnosis of dementia. It assesses the memory, concentration, orientation, language and visual-spatial skills to determine the progression and severity of the disease. The higher the MMSE score, the better the cognitive function.
  2. Improve behavioural symptoms. More than 80% of dementia patients showed reduced incidences of hallucination. In addition, more than 50% of patients demonstrated improvement in delusional states, depression and hygiene awareness. Furthermore, improvement of sleep disorder and urinary incontinence were also observed among the patients.
  3. Improve facial expression and emotion. More than 90% of patients showed an improvement in expressing emotions with bright facial expression. Moreover, they are also more aware and concerned about their surroundings after ingesting Scallop-derived PLASMALOGEN.

 

Real case studies of Scallop-derived PLASMALOGEN on dementia patients

The clinically proven results are recognized by dementia specialists in Japan who recommended it as a natural therapy for their Alzheimer’s and dementia patients. I am enthusiastic to share some of the case studies with you here.

Case 1: Improvement from moderate to mild stage of dementia

Kiyoshi was diagnosed with semantic dementia for 3 years, which is characterised by language difficulty such as inability to understand words. His MMSE score before taking Scallop-derived PLASMALOGEN was just 18 points, indicating moderate stage of dementia. However, his MMSE score increased to 23 points (mild stage) just 1 month after taking Scallop-derived PLASMALOGEN. Watch video at:

https://www.facebook.com/plasmalogens/videos/1745610769061115/

 

Case 2: Most amazing improvement seen by research team

This 81-year-old Japanese woman was diagnosed with Lewy body dementia which is characterised by symptoms such as hallucinations. Before the intake of Scallop-derived PLASMALOGEN, the patient was not very responsive when the doctor greeted her and sough permission to examine her. Remarkably, she showed dramatic changes just 2 weeks after the administration of Scallop-derived PLASMALOGEN. Watch video at:

https://www.facebook.com/plasmalogens/videos/1743594745929384/

I am very honored for the privilege to be a part of this project to help Alzheimer’s and dementia sufferers improve and regain their quality of life and dignity. We hope to empower caregivers whose lives are also impacted by the immense physical, mental and financial stress of caring for their loved ones. I sincerely hope this article will be able to give caregivers the hope, strength and courage to go through this unimaginably difficult time. With this available option of natural dietary supplementation, Alzheimer’s and dementia are no longer fatal. This latest development will transform the lives of millions of people. If you are able, please like our Facebook page or share this article, videos or website to save more lives.

You can visit http://plasmalogen.me/ if you are interested to find out more about clinical trials of Scallop-derived PLASMALOGEN. Please feel free to email me at crystalgoh@plasmalogen.me if you need any further information. I also wish to share with you that The 1st International Plasmalogen Symposium will be held on November 7 and 8, 2016, in School of Medicine, Kyushu University in Japan. Please visit http://plssympo.com/index.html for more details.

Thank you, Dr. Goh, for contributing this most relevant information!

 

 

Many of us caregivers live with the thought that we may one day have to deal with dementia ourselves. New research data released at the 2016 Alzheimer’s Association International Conference July 24-28 in Toronto indicates that we may be able to exert some control over what happens as we age.

New research reported at the recent Alzheimer’s Association International Conference suggests that working at a job that requires complex thinking skills or involves mentoring other people may help protect us against Alzheimer’s disease.  In essence people who engage in a mentally stimulating lifestyle, which includes more formal education, complex work environments and engagement with people, may be associated with reduced cognitive decline and dementia as we age.

On Tuesday, July 26th, I had the privilege of speaking with Dr. Heather Snyder, Ph.D., senior director of medical and scientific operations for the Alzheimer’s Association.  She oversees the Association’s international research grant projects, the mechanisms through which the Association funds research applications.

To watch my interview with Dr. Snyder, click here and then click on Dr. Snyder’s photo.

The Alzheimer’s Association is the leading voluntary health organization in Alzheimer’s care, support and research.  Their mission is to eliminate Alzheimer’s disease through the advancement of research, to provide and enhance care and support for all affected, and to reduce the risk of dementia through the promotion of brain health.  Their vision is a world without Alzheimer’s disease.

To access more information about research reported at the Alzheimer’s International Conference in Toronto, go to http://www.alz.org.

For many of us who have had one or more family members afflicted with dementia, we carry within our psyche the realization that we may one day have to deal with this condition in our own lives.

While on holiday with family at the New Jersey shore, I read with great interest a message from Miriam Rule, Promotions Officer at the University of Tasmania, about a free online course on preventing dementia.

The course entitled, Massive Open Online Course on ‘Preventing Dementia’, is a FREE five-week fully online course that draws on the latest scientific evidence, as well as the expertise of leading researchers in dementia prevention, to outline and discuss the key risk factors for dementia that are potentially modifiable.

The MOOC has over 70,000 participants from around the world.  MOOC is an acronym for Massive Open Online Course – a recent global educational development that has been embraced by key universities and learning institutions around the world, such as the University of Tasmania through its Wicking Dementia Research and Education Centre.

What really caught my eye when perusing the course brochure is that latest research estimates that approximately a third of dementia cases may be preventable by attending to potentially modifiable risk factors.  This is a great opportunity to learn from home at your own pace and engage with a community of participants from across the globe without exams or assignments.

The course actually began on July 12, but I believe you will still be able to register and garner much useful information by joining the class before its second session scheduled for July 19.

Click here to access the course brochure and register.

Our thanks to Miriam Rule for informing us of this awesome opportunity.

 

 

 

Around 18 million Americans suffer from dysphagia, a swallowing disorder, which can make every meal and sip of water feel like drowning, as the disorder makes swallowing difficult.  The main risk is aspirating or inhaling food/liquid into the airway and lungs, which then can cause pneumonia.  These individuals must rely on thickened liquids, but options are limited and often unappealing.  As a result more than 200,000 short-term hospital stay patients with dysphagia are discharged with dehydration each year.

I well remember my mom’s reaction to the thickened drinks served on her nursing home tray.

In the brief video below I am pleased to have you meet Jennifer Baquet, CCC-SLP, a senior clinician with Language Fundamentals, which provides services at the Amsterdam Nursing Home in New York City.  Jennifer was part of a team at Amsterdam that helped develop and implement an innovative dining service program for patients with dysphagia.

They created new and popular drink flavors like kiwi strawberry, and even were able to serve broths or a resident’s own favorite tea.

Click here to watch the video.

The two suggested websites for creative drink recipes are http://Thick-It.com and the American Speech-Language-Hearing Association at http://www.asha.org.

 

 

 

 

Glad to be Back!

 

You who have been regular visitors to Memories from My Life know that I have gone through a dry season of no new content for quite some time.  I want to express appreciation for your understanding over the past several months since my husband’s sudden passing.  His death on March 19th after our relationship of nearly 50 years left me with a heartache that at times has seemed unbearable.  Spiritual strength along with the loving support of family and close friends has helped me get through.

Ours was not a perfect marriage;  we had good times and the not so goods.  But we shared life together, the mountaintops and the valleys.

Through this period of reflection I have invested in one-on-one grief counseling.  Through my counselor I was referred to the book, The Five Love Languages by Gary Chapman.  In the book the author talks about the five common ways love is shared between partners:  1) through words of affirmation; 2) through sharing quality time; 3) through receiving gifts; 4) through acts of service; and 5) physical touch.  I learned that sometimes the way one partner shows his/her love may not be what his partner would like to receive and vice versa.  How I wish I had know about this book earlier in my marriage.

On a brighter note I am privileged to let you know that Memories from My Life has again this year been recognized in 2016 as being one of the Top 25 Alzheimer’s Blogs by Healthline.com!

I would highly encourage you to subscribe to Healthline’s flagship newsletter, Your Guide to Wellness.  As the fastest growing consumer health information site — with 65 million monthly visitors — Healthline’s mission is to be your most trusted ally in your pursuit of health and well-being.

Along with being a goldmine for health information to all ages, Healthline publishes real stories from real people.  A few examples follow:

–  What it means to have a parent with bipolar disorder…

–  Managing depression after divorce:  What you can do…

–  How yoga can impact migraine relief…

–  Parenting:  How to take full advantage of summer with your kids…

–  Pregnancy:  7 tips for coping with anxiety during pregnancy…

Go to:  http://www.Healthline.com

 

 

 

Devastating Loss

Dear Readers,

With great sadness I want you to know that my husband died March 19 of severe spinal cord injuries sustained from a fall on March 5.

Jack was 76 years old and had weathered three strokes over the past ten years along with a knee replacement and gall bladder surgery with complications.  In spite of his fragile condition we were able to enjoy a number of trips.  A former physicist and mechanical engineer, his intellectual curiosity eventually focused on ancient history, specifically a system of ancient writing found worldwide, coined by him as Earth Mother Sacred Language.  His passion for EMSL symbols took us on several wonderful trips to great museums in Europe, Mexico, and Canada.  Meticulously organized, he amassed an extensive collection of research and insights that epigraphers who follow in years to come may build from.

Now, to tell you what happened on March 5.  The day was a Saturday and it had been rather full.  We were preparing to meet good friends for dinner across town that evening, and I wanted to make the trip count by getting a birthday gift certificate for our younger son.

My husband was so happy about being recently certified to participate in a health club a short distance from our home.  He had been with a trainer earlier in the week and we had also gone midweek to participate.  Eager to build a bit more strength he wanted to make it a third time for the week.

So around 4:15 in the afternoon we drove to the center.  (I had been doing all the driving for us for quite some time.)  This day we needed to meet our friends for 6:30 and I was not quite ready for the evening.  So Jack said, “Just drop me off and then pick me up.”  That at the time sounded reasonable to me.  So I did.  As he left the car I said, “Don’t take any chances.”

As I was leaving the house to pick him up, a call came from the center that my husband had fallen and was being taken to the nearby emergency room of the hospital.

He had had other falls over the years, so I didn’t feel unusually anxious, thinking he might probably need a few stitches.  But this was way different.  At the hospital he told me he had done his usual trips around the track, then the four easy machines on the main floor.  Lastly, he told me he got on the treadmill and that was it.  He told me, “I’m so disgusted.”

Those were really the last words he was able to utter, for a respirator was placed in his throat for extensive MRIs then surgery later that evening.   The surgery according to doctors was successful, but what followed was paralysis of his limbs and eventually his diaphragm.

I stayed with him in his room, doing the best I could to make him comfortable.  Doctors told us he would never be able to walk again.  But he could have a tracheostomy and work toward being weaned from it gradually.  He could choose Hospice or opt to have the trach put in.  He chose to live, and I was encouraged.

But complications ensued during the second week further weakening his body.  His mind, however, was clear and he was very present to what was happening.

The doctor spoke to us as a family later that week, telling us my husband was dying.  At this point we did what we could do, wanting him to hear from friends and colleagues who held him in high regard.  So I made phone calls and emails to people around the country, and they each called back and were able to speak to him via my cellphone speaker.  Each of us – our sons and myself had time to tell him as best we could how much he meant in our lives.  And we said goodbye that evening.

Now, my family is back at their homes for a few days and the house is all too quiet.  I continue to encounter raw moments of despair, wishing I could have done things differently that Saturday afternoon.  All I have is turning my guilt over in  prayer, trusting that I can be of good to my children and grandchildren in future days.  Nothing else really matters except love to be shared.

In a few days family will return and we will comfort one another with warm memories of good times shared with Jack over his lifetime.

I realize you may have endured what I am experiencing at this time.  It is a part of the cycle of life.

I want to thank you for allowing me to tell you what happened.  There are a number of writers and experts in their fields who have sent articles and information for sharing with you.  I will do my best to represent them as soon as I am able.

In the early stages of dementia the ability to manage finances often can become impaired.  My mother used to pride herself on never needing a calculator, enjoying the exercise of adding up ‘in her head’ columns of numbers when preparing tax records.  In her healthy life she was meticulous about her financial affairs.  However, when her math skills began to slip, she turned to my brother, who lived nearest to her, for assistance.

Other families may not be so lucky.  If a parent or other loved one develops dementia, a risk that grows with age, finances can present a big problem.  In fact you may have to step in to make sure your mom or dad doesn’t rack up credit card debt or even go broke.

That’s what happened to Kay Bransford, an author and entrepreneur in Virginia, after her mom and dad both developed dementia.  When a home contractor tried to charge her parents more than $5,000 for needed repairs, more than five times the going rate, Bransford acted quickly to cancel the contract.

Because of the dementia her parents also went from donating once a year to their favorite charity to making many donations of $10 to $25 in response to mail solicitations that would thank them in advance for their pledge.  “I know my parents never pledged,” said Bransford, who started the blog Dealing with Dementia.  “It was distressing.”

Carolyn Rosenblatt, a registered nurse, elder law attorney and consultant, who runs the website http://www.AgingParents.com has much to say about dementia and debt:

“Dealing with a loved one with dementia and debt is tough work. If someone with dementia builds up a credit card or other debt, you might be able to get it forgiven, but it often takes some legal help.  Thousands of dollars may be at stake.  And, yes, calling the credit card company is worth it.  But be prepared for long waits, transfers to other departments, stonewalling, and delayed responses.  They want you to give up and just pay the entire bill.”

Rosenblatt advises:  “It’s better if things never get to that point.  Stay alert for signs of possible dementia and offer to help manage a parent or spouse’s finances early.  Be proactive.  Some adult children say, ‘We’ll just wait and see what happens,’.  What happens is you get wiped out financially.”

Rosenblatt offers six steps to take if a parent or other loved one has dementia:

1.  Face the problem.  Some adult children and even spouses, when they first see signs of memory loss, dismiss the problem.  Rosenblatt says, “When a person can’t remember a conversation they had yesterday, and it happens over and over, that’s not normal aging.”

2.  Know how dementia can affect financial skills.  Even in the early stages of dementia a person may not be able to deal with financial tasks such as checking a credit card bill and getting any errors corrected.  As a result, a loved one could end up paying recurring monthly charges — such as for subscriptions they never purchased or free trials they forgot to cancel.  It’s also common to have trouble paying bills — or to pay one bill twice or more and forget to pay another one.

3.  Offer to help with bills.  You can say, “Mom or Dad, I’m a little worried because I noticed you’re having trouble keeping track of things.  Can I help you pay the bills?”  That way you can verify that all bills have been paid correctly and on time, making sure utilities or insurance don’t get canceled for nonpayment.

One tactic, especially if your relative doesn’t use online banking, is to set up online access to credit card and bank accounts for yourself, and let your loved one continue to receive paper statements in the mail.

4.  Get durable power of attorney.  It’s important to get financial, durable power of attorney, which gives you the ability to make financial transactions for your loved one.  If your parent or loved one is cooperative, it’s easy, and you can get free forms online so you don’t have to pay an attorney to help.  If your parent or loved one is not cooperative and you can’t get power of attorney, then you may need to go to court to get guardianship or conservatorship.

5.  Enlist help.  If your loved one is reluctant to let you help with the bills, get help from a clergy member, another relative, or a mediator.  In Kay Bransford’s case her parents’ doctors encouraged them to have a loved one help manage their money.  When her parents forgot how to deposit cash and checks, they added their daughter to their bank account.  Bransford says, “From there I could monitor what was going on.”

6.  Take away the credit cards.  It can be difficult to take away a parent’s credit cards, especially when they’re very lucid on some days, says Sheldon Goldman, a certified financial planner in California who works with senior clients.  Goldman has a client whose father has memory issues, pulling out his credit cards to make donations to every charity he sees on TV and to send flowers to friends and family.

Kay Bransford faced the same issue when her parents, who normally used checks, pulled out plastic to sign up for an expensive magazine subscription.  She eventually took their credit card away and replaced it with a debit card tied to an account that contained only a few hundred dollars.  “I learned to find small ways to work around issues,” she says.

Appreciation for this article is extended to Allie Johnson, an award-winning freelance writer and contributor to CreditCardGuide

 

 

 

   

 

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